As a typical tonic medicine found in Chinese medicine and other healing traditions in Asia, the clinical utility of He Shou Wu largely depends on processing methods. The hepatotoxicity of HSW is not easily detected when used at recommended doses and when properly processed as a decoction. In the Chinese Pharmacopoeia the predetermined daily dose of decocted He Shou Wu is 3-6g, about 1/2-1tsp. It can be added to tea, coffee, or your favorite latte.
We recommend everyone listen to their body intuitively; follow the dosage that resonates the most with you.
The main chemicals responsible for the hepatotoxicity of HSW are free anthraquinones such as emodin and physcion [R], which are at higher percentages when consumed in its raw form. Because it also may mimic estrogen in the body, it is not recommended for those dealing with estrogen positive cancers, or excessive estrogen count overall.